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Like insulin, IDE is structurally distinctive, consisting of two bowl-shaped halves connected by a flexible linker that can switch between "open" and "closed" states [9].
SEM imaging enables researchers to distinguish two structurally distinctive populations of PG aggregates [ 54].
Inter-facet orthogonality, on the other hand, demands that each of the n facets are structurally distinctive and functionally apart from each other.
Through these searches we were able to identify around ten previously unknown families/superfamilies of domains containing the β-GF, including certain structurally distinctive variants.
scr5583, sar2652, and svr5279 shared extensive sequence identity, and were predicted to have a structurally distinctive C-rich (67%) terminal loop.
These clones may be of interest because they might contain large repetitive and structurally distinctive regions with extremely high GC content.
Similar(52)
Ruthenocene is analogous to ferrocene structurally, but exhibits distinctive redox properties.
The combination of sucrose and starch in the presence of surface-adsorbed salivary α-amylase and bacterial glucosyltransferases increase the formation of a structurally and metabolically distinctive biofilm by Streptococcus mutans.
Furthermore, we have collected evidence that the interaction of sucrose and starch through surface-adsorbed salivary α-amylase and Gtf enzymes (particularly GtfB) modulates in situ the development of biofilms that are both structurally and metabolically distinctive [15], [16].
In principle, it should be possible to enhance the activity of insulin by inhibiting its catabolism, which is mediated primarily by insulin-degrading enzyme (IDE), a structurally and evolutionarily distinctive zinc-metalloprotease.
In other words, an interaction is distinctive when structurally similar drugs tend to behave oppositely on the same proteins.
Related(19)
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