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Temporally stable heterogeneity in the prevalence and aetiology of putatively contaminant-induced biomarkers has been identified around UK coastal waters.
The results described so far reveal that stable heterogeneity can arise simply as a consequence of the fact that growth factors are diffusible public goods.
Stable heterogeneity is a typical outcome of the dynamics, while a pure equilibrium of nonproducer cells is possible under certain conditions.
Here, we show that stable heterogeneity for the production of growth factors arises as a direct consequence of the fact that growth factors are nonlinear public goods.
First, PMC42 exhibited stable heterogeneity of at least eight morphologically distinct cell types arising from in-culture differentiation of both epithelial and myoepithelial progeny all the way to terminal differentiation and cell death.
Stable heterogeneity is more likely to occur for low levels of h (that is, when few producer cells are enough to confer a benefit to the whole group; Figure 2).
Similar(51)
Spatial and thermal stable heterogeneities have been generated only in HD-PE modified with high energy electrons under the dynamic conditions of melt mixing.
Temporally stable spatial heterogeneity would be expected to lead to spatial heterogeneity in the acquisition of immunity, which may be evidenced by variation in the age profiles of children with febrile malaria.
Both mechanisms produced stable phenotypic heterogeneity, but the distribution of the cell types was different.
These results show that the microscopy system and the data analysis were sufficiently sensitive and stable for resolving heterogeneity in the luminescent emission from different V.fischeri cells.
To test whether the results were stable with known heterogeneity, we performed sensitivity analyses.
Related(20)
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