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As shown in Fig. 2B, incubation with 100 µM DIDS did not affect the fluorescence signal of control cells, demonstrating that the endogenous channels were not blocked by DIDS at the concentration used.
Simply comparing the BOLD signal of control and autistic people may not be meaningful.
The background fluorescent signal was determined by measuring the signal of control isotype-matched IgG binding to cells.
Statistical analyses were performed comparing each signal of patient's fibroblasts RNA with the corresponding signal of control RNA by two different approaches.
Difference in gene expression was calculated as fold change, dividing the signal in individual CRC samples of interest over the average signal of controls.
Here, in this work, we are analysing the ERG signal of controls, congenital stationary night blindness (CSNB), and cone-rod dystrophy (CRD) with the nonlinear chaotic perspective of analysis.
"Policing is always about communication and exhibiting signals of control," says Leah Moyle, one of the authors of the study.
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Terminologist and Q/A Analyst @ Translation Centre for the Bodies of the European Union