Sentence examples for serum cmax from inspiring English sources

A computer-controlled syringe pump (402 Dilutor Dispenser; Gilson S.A, Villiers-le-Bel, France) allowed the simulation of drug concentrations by infusion of the drug into the central compartment until the maximum concentration achieved in serum (Cmax) was reached.

intravenously, corresponding to a serum Cmax of 90 100 μg/ml.

To examine the impact of age and sex on the clinically relevant ocular and systemic exposures, the magnitude of their covariate effect on ocular Cmin, cumulative AUC, serum Cmax, and cumulative AUC was examined.

For daily and twice-daily AMK, the serum Cmax were 1.3 and 1.8 μg/ml (respectively) on day 1, and 2.3 and 3.2 μg/ml on day 3. Mean trough levels were 0.87 and 1.49 μg/ml.

The percentage of the time in which KAE609 plasma concentrations remained at >2× the IC99 within 48 h (% T>TRE) and the area under the concentration-time curve from 0 to 48 h (AUC0 48)/TRE ratio correlated well with parasite reduction (R = 0.97 and 0.95, respectively) but less so for the maximum concentration of drug in serum (Cmax)/TRE ratio (R = 0.88).

Twelve subjects in each group (obese and normal weight) allowed the detection of a 19% difference in 12-h drug exposure (area under the concentration-time curve from 0 to 12 h [AUC0-12]) and a 16% difference in the maximum concentration of drug in serum (Cmax) for the 75-mg dose and a 22% difference in AUC0-12 and 24% in Cmax for the 150-mg dose.

Maximum serum concentrations (Cmax) and time to Cmax (tmax) were taken from the measured serum concentration data.

Introduction: Amikacin infusion requires to target a peak serum concentration (Cmax) 8 10 times the minimal inhibitory concentration, corresponding to a Cmax at 60 80 mg L−1 for the least susceptible bacteria.

DOX-h-LA showed the greatest values for bioavailability (199.48%); maximum serum concentration (Cmax) value was 2.8 ± 0.3 with a time to reach Cmax (Tmax) of 2.11 ± 0.12 h and an elimination half-life of 133.61 ± 6.32 h.

Dox-pol showed the greatest values for relative bioavailability (548%); maximum serum concentration (Cmax) value was 1.3 ± 0.7 μg/mL with time to reach the Cmax (Tmax) of 5.9 ± 1.7 h, area under the curve (AUC) of 17.0 ± 2.2 μg h/ml and elimination half-life (T½ β) of 4.9 ± 1.0 h.

Maximum serum concentrations (Cmax) after i.m. were higher than s.c. administration (p = 0.034).