Sentence examples for blood cmax from inspiring English sources

For the male volunteer, the maximum concentrations in blood (Cmax) occurred shortly after the end of exposure (tmax ≈ 30 min), with a value of 0.8 ng/mL.

Visual inspection of the mean blood [H]-PG545 concentrations vs time curve data showed that the mean blood Cmax values were in the range 25.9 29.0 μg ml−1 and the corresponding mean Tmax values were in the range 2 6 h.

The maximum blood concentration (Cmax) of everolimus was 24.4  μg l−1 and it was achieved at a median time to Cmax (tmax) of approximately 4 h, with a wide range of 0.98 6.02 h.

HCQ pharmacokinetic parameter estimates (peak blood concentration, Cmax; trough blood concentration, Cmin, average blood concentration, Cavg, area under the concentration-time curve, AUC) from these simulations were used to explore PK-PD relationships.

HCQ pharmacokinetic parameter estimates (peak blood concentration, Cmax; trough blood concentration, Cmin, average blood concentration, Cavg, area under the concentration-time curve) from these simulations were used to explore pharmacokinetic-pharmacodynamic (PK-PD) relationships.

HCQ pharmacokinetic parameter estimates (peak blood concentration, Cmax; area under the concentration-vs.-time curve, AUC) from these simulations were used to explore pharmacokinetic-pharmacodynamic (PK-PD) relationships.

The PK-PD relationship between HCQ and AV accumulation was first investigated by using an exploratory classification tree (Salford Predictive Modeler Builder v6.6), which identified a threshold effect of the peak blood concentration Cmax.

Peak plasma or blood concentrations (Cmax), overall drug exposure (area under the plasma concentration vs time curve; AUC) and terminal plasma half-life (t1/2) were calculated using non-compartmental methods according to the Bayer guideline 'Harmonization of Data Evaluation in Pharmacokinetics – A Task Force Report – ' (1992 R-Report No. R-5747 and 2000 Amendment A to Report No. R-5747).

The study found that the time at which Cmax (blood plasma concentration) was reached was much higher for liposomal irinotecan compared to normal irinotecan (10.2 compared to 2.1 h after infusion), showing that liposomal irinotecan stays active in the bloodstream for longer.

The mean pharmacokinetic parameters of MZT, administered through the integrated MN, was determined by a non-compartmental analysis of the whole blood, where the Cmax was 4.64 ± 1.05 μg ml−1 at a Tmax of 4.67 ± 1.15 h.

The study measures included Cmax (maximum blood concentration), AUC (area under the blood CyA concentration versus time curve, 0 to 4 hours) and actual time concentrations at individual sampling times.