Encryption that renders genes substantially different from homologs in other species includes sequence substitution, insertion, deletion, fragmentation plus scrambling, and invasion by mobile genetic elements.
Recently, an interesting question has emerged in the evolutionary interpretation of sequence substitution data as evidence of amino acid selection pressure.
The validity of the energy functions has been further examined in a series of sequence substitution studies based on the structures of DNA bound to polyamides that have been designed to recognize the minor-groove edges of Watson-Crick basepairs.
We constructed the parameter and data file in BEAUti v1.5beta2, selecting the general time reversible (GTR) with invariant sites (+I) and gamma distribution of site changes (+G) model of DNA sequence substitution.
Relative rate tests comparing DNA sequence substitution rates indicated that no significant differences exist in the rate of DNA sequence evolution among putative saltational and non-saltational sister taxa (P values ranging from 0.26 0.74).
We examined non-synonymous (KA) and synonymous (KS) coding sequence substitution rates, as well as intron sequence substitution rates (KI), from human-chimpanzee orthologues [ 6].
