Sentence examples for secondary passage from inspiring English sources

Secondary passage of brain homogenates was conducted from animals in all reaction groups.

Secondary passage of brain homogenate from these animals was free of scrapie infectivity (survival>200 days).

All these parameters were similar in the transmission studies of primary and secondary vCJD in transgenic mice, indicating that the strain properties of the vCJD agent have not changed significantly following secondary passage in humans.

This suggests that the risk of onward transmission of vCJD through other routes, for example contaminated surgical instruments, have not been increased by adaptation of the infectious agent to humans following secondary passage.

Although it has been hypothesized that adaptation of the BSE agent through secondary passage in humans may result in a greater risk of onward transmission due to an increased virulence of the agent for humans, our data presented here in two murine models suggest no significant alterations to transmission efficiency of the agent following human-to-human transmission of vCJD.

Secondary passage of vCJD infection via blood transfusion in an MM codon 129 genotype individual results in a clinical disease phenotype and pathological characteristics that are similar to vCJD derived from BSE. [4] In this paper we confirm that the agent strain properties of primary and secondary vCJD cases are similar in transmission studies in transgenic and wild-type mice.

However, it should be mentioned that the spheres from tertiary passages was smaller than from first and secondary passages.

It is likely that secondary passaging promoted further development of the NSCs from the ES cells.

More spheres were generated only when BIO treatment was present during secondary passaging.

Secondary passages were performed by using PrPres-negative or PrPres-positive individual mouse brains.

Secondary passages were performed with brains of mice that died at various time points.