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Exact(51)
Ring activation is followed by ring cleavage catalyzed by specialized dioxygenases (intra- and extradiol dioxygenases) that start the lower pathways.
Reduction and ring cleavage produces the tail-to-tail linked product.
The structures of ring cleavage compounds are indicated in boldface.
A parallel transformation involves benzopyran moiety with the ring cleavage.
Metabolic intermediates that can be subjected to aromatic ring cleavage are indicated in dashed boxes.
Cresol, nitrotoluene and ring cleavage products are formed from these two reaction pathways.
Similar(9)
Cross-ring cleavage is the dominant fragmentation pathway in ECD.
Then, all these isoflavone aglycones are further transformed by C-ring cleavage and dehydroxylation reactions in the colon.
In reverse, XIAP can be cleaved by caspase-3 into BIR1-2 and BIR3-RING cleavage fragments [ 33].
Cross-ring cleavage ions at m/ z 505.2, 533.2, 723.3 and 1349.5 could be identified, though they were relatively weak (see Figure 4, indicated with black arrows).
They result from naphthalene hydroxylation and ring-cleavage by action of oxygenated radicals.
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