Sentence examples for nucleus cleavage from inspiring English sources
Thus, release of cytochrome c is responsible for the observed caspase-3 activation, and nucleus cleavage.
Additional studies indicate that BI-69A11 decellses cell viability mainly by triggering apoptosis, as evident by an increase in sub G0/G1 population of cells, characteristic morphological changes of apoptosis in the nucleus, cleavage of PARP and increase in BAX as well as an increase in TUNEL-positive cells in HCT116 and HT29 cells.
The C-terminal region of Pak2 (213–524) can translocate into the nucleus after cleavage by Caspase 3 in response to apoptotic stimuli [20].
This pQ-H-pQ sequence is part of the Notch intracellular domain (NICD), which is translocated into the nucleus upon cleavage.
From these perinuclear mitochondria, AIF can rapidly translocate into the nucleus after cleavage from the OMM by calpain-1, which is also localized in the nucleus and is activated by elevated levels of Ca2+.
Piceatannol treatment attenuated the intracellular accumulation of ROS induced by treatment of PC12 cells with amyloid beta, inhibited amyloid beta-induced apoptotic features including internucleosomal DNA fragmentation, nucleus condensation, cleavage of poly(ADP-ribose) polymerase (PARP), and activation of caspase-3.
Sox2 protein was located in nuclei in cleavage stage embryos, although nuclear staining at the 2-cell stage was weak and cytoplasmic staining was observed.
A closer examination of mitoses that occur in the presence of MMS or the resulting interphase nuclei in cleavage stage Hydractinia embryos revealed surprisingly few problems.
This spatial domain includes 30 nuclei in cleavage cycle 13 and 58 in cycle 14A.
ATF6, the third pathway of the UPR (Figure 1), is another transcription factor that translocates to the nucleus after its cleavage under ERS conditions18,37.
Inactivation of topoisomerase II prior to anaphase prevents chromosome segregation, but not cytokinesis, resulting in the "cut" phenotype (abscission of the nucleus by the cleavage plane).
