Sentence examples for replication factory from inspiring English sources

We found that in unperturbed conditions Pol κ-depleted cells have proliferative defects, altered replication factory dynamics, spontaneous replication stress, and under-replicated regions which are transmitted to daughter cells.

In the latter case active genes may need to disengage from RNAPII factories to shuttle to a nearby replication factory.

Again, we checked that the change in replication factory dynamics was independent of endogenous oxidative stress.

Pol κ depletion also affected replication factory dynamics over the duration of S phase.

The data are inconsistent with models in which replisomes associated with sister forks act within a fixed replication factory.

Pol κ-depleted cells contained predominantly middle and late phase replication factories, with fewer cells displaying early replication factory morphology compared to control cells.

ZIKV is a positive-strand RNA virus replicating in virus-induced membranous replication factories (RFs).

There is, e.g., no reason known to us for one to expect that major processive DNA polymerases change the neighbor-base-dependence of their, in any case very low, mutagenicities when they replicate regions of different GC (but different replication factories could be used for early and late replication [20].

Ad DNA replication is the result of an organized interplay between viral proteins, cellular factors, and viral template DNA at distinct sites within the nucleus termed replication factories.

Now it would be easy to imagine a scenario though difficult to unequivocally prove where much more efficient genomic colonists started to use larger "resource" vesicles as replication factories that would eventually gain greater autonomy.

Some of these membranous structures resemble replication factories (Fig S3).