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Modification of the protein interaction sites in the 3' non-translated region yielded viral RNAs that were replication deficient.
Furthermore, Adv-5 is replication deficient.
The shuttle vector was used to prepare replication deficient adenovirus using the AdEasy system (Stratagene) as previously described [14], [15].
Deletion of E1A renders adenoviruses replication deficient.
Adeno-associated viruses (AAVs) are single-stranded DNA parvoviruses that are replication deficient [ 19].
Mice were immunized with a recombinant replication deficient adenovirus serotype 5 containing the 85A antigen from M. tuberculosis (Ad85A) [ 5].
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Chapter 6 addresses the different types of alphavirus vectors (replication-deficient, replicating and DNA-based).
Cenna, J. et al. Replication-deficient rabies virus-based vaccines are safe and immunogenic in mice and nonhuman primates.
Selvapandiyan, A. et al. Intracellular replication-deficient Leishmania donovani induces long lasting protective immunity against visceral leishmaniasis.
Papaneri, A. B. et al. A replication-deficient rabies virus vaccine expressing Ebola virus glycoprotein is highly attenuated for neurovirulence.
Adenoviral p53 (Adp53) is a replication-deficient adenovirus containing human p53 cDNA.
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