Ai Feedback
Exact(34)
Histone modifications are the ideal candidates to inform the replication apparatus about the nature of the chromosomal environment.
We reasoned that, since aberrant DNA duplication is so prominent in TD cells, any such anomalies would be likely to directly involve components of the DNA replication apparatus or indirectly impinge on them.
We therefore propose that methylation of H3 K36 is part of a signaling-network of histone modifications that informs the replication apparatus about its choice of origin usage by either favouring or inhibiting its interaction with chromatin (Fig. 7).
Not surprisingly, they included many proteins involved in basic cellular processes, such as ribosomal proteins, components of transcription, translation and DNA replication apparatus, cytoskeletal proteins, histones, proteins involved in the secretory pathway, protein folding, protein sorting and ubiquitin-mediated proteolysis and enzymes involved in primary metabolism.
A virus take over of the replication apparatus could have created a bacterium with a novel replication apparatus, that's all.
RNA viruses use pseudoknots for hijacking the replication apparatus of the host (Brierley et al., 2007).
Similar(26)
It has been hypothesized that the AbSV progenitor was a secondary parasite that shared some replication apparatuses with the same multiplication factory as an archaeal endosymbiont residing in a eukaryotic cell, and HGTs facilitated acquisition of these genes that endowed the recipient with an adaptive advantage from the ingested DNA.
This model, offered as an alternative to non homologous gene replacement, elegantly explains the disparities observed between the bacterial and archaeal/eukaryotic replication apparatuses.
DNA replication is an essential process and is generally conserved across all three domains of life, making use of two different DNA replication apparatuses (bacterial-type and eukaryotic-type) [ 1, 2].
Such a mechanism provides a straightforward model of primer hand-off in eukaryotic replication, by removing the need for molecular transactions between primer-bound Pol α and the replicative apparatus deputed to leading and lagging strand synthesis.
At the time of the origin of life, this complex replication and transcription apparatus could not have been in operation.
Related(20)
replication machinery
replication material
application apparatus
playback apparatus
replication machine
replication tool
mirror apparatus
simulation apparatus
replication materials
playing apparatus
replication machines
replication tools
replication mechanism
replication placement
replication recombination
replication fork
replication origin
replication rate
replication classification
replication problem
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com