Sentence examples for repeated mutation from inspiring English sources

This cycle of repeated mutation and selection of the gene variants via the phenotypes they generate is at the core of evolutionary theory.

Some sequences shared a particular stop codon, where the repeated mutation giving rise to the stop codon could be traced to a common 454 error pattern.

Repeated mutation analysis from original DNA was performed on tumors to confirm mutations.

Additionally, 79 mutated genes have been found in nine PCTs where TP53 was the only repeated mutation.

In order to compensate at least partially for the possibility of repeated mutation at the same site, a number of different distances are in use, based on different models of mutation.

Detection of its repeated mutation in independent tumors would indicate positive selection for cells that acquire the mutation, but its presence at levels significantly lower than the most abundant mutations within a tumor would suggest acquisition at a stage of tumor development after significant clonal expansion had already occurred.

Traditionally, MK production has been improved through the development of better strains by a repeated mutation-selection approach.

DOI: http://dx.doi.org/10.7554/eLife.04279.010 Repeated mutations to the same loci in independently evolved replicates strongly suggested that the mutations were causal.

We searched for repeated mutations that are unique or that have significantly higher frequencies in BEN patients as compared to individuals from European populations.

A similar analysis carried out counting the repeated mutations the number of times that they appear in each population led to different results.

In fact, complete sequence analysis allows the appreciation of the effects of rare or repeated mutations unaccounted for in haplogroup analysis (Rollins et al., 2009).