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That is, rather than focusing upon the ecological interactions of a species as a whole, one could separate a species' total niche into different phenotypic components and then determine how these phenotypes influence fitness in varying environments (Roughgarden, 1972; Bolnick et al., 2010).
We conducted association analysis to 1) replicate associations with reading and nonword repetition measures, 2) dissect the phenotypic components of such associations by testing different but related quantitative phenotypes to pinpoint the underlying cognitive deficit(s), and 3) test for pleiotropic effects across reading- and language-related measures.
In vivo dissection of the CNV showed discrete contributions of the planar cell polarity effector SCRIB and the splicing factor PUF60 to the syndromic phenotype, and the combinatorial suppression of both genes exacerbated some, but not all, phenotypic components.
In consequence, sex-limited patterns of hormone production would be reflected differently in the differentiation of different phenotypic components (neuron numbers versus synapse density) of the vocal areas, if these phenotypic components differ in their hormone-sensitivity.
In addition, we cannot ignore the possibility that RTN4R deficiency contributes to other phenotypic components not assayed here.
Taken together with our prior human genetic data and results in other literatures, rSey2/+ rats likely have some phenotypic components of autism.
Similar(40)
Because examination of CYP1A2 activity in relation to mammographic density was not a goal of the original study, patients were subsequently mailed a letter describing the goals of the phenotypic component of this study, and written consent was obtained to phenotype CYP1A2 activity.
Sperm motility is one phenotypic component of sterility.
Cough severity, a common disabling phenotypic component of IPF, is significantly associated with the presence of the minor allele of a MUC5B promoter polymorphism.
Our observation of the possible relationship between MUC5B and cough suggests a possible influence of this polymorphism and suggests that the presence of the minor allele in MUC5B may account for a specific phenotypic component of IPF.
Furthermore, our results are the first of which we are aware that support the suggestion that in studies of sexual selection, genetic quality of males is best estimated as the breeding value for total fitness, rather than estimates of specific phenotypic fitness components [40].
Related(19)
genotypic components
phenotypic methods
phenotypic compounds
phenotypic constituents
phenotypic factors
phenotypic scores
phenotypic responses
phenotypic traits
phenotypic variations
phenotypic changes
phenotypic evaluations
phenotypic data
phenotypic markers
phenotypic frequencies
phenotypic analyses
phenotypic alterations
phenotypic correlations
phenotypic characteristics
phenotypic features
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