Sentence examples for mutations that trigger from inspiring English sources

If researchers can trace the bacterium's evolutionary history, they might be able to identify the key mutations that trigger virulence or adaptation to different habitats, for example.

The panel also wants to build a completely new human tumor database that would probe not only mutations that trigger cancer in a person, but the 3D complex of immune and other cells surrounding a tumor that help sustain its growth and allow it to spread.

Mutations that trigger activation of Akt would also stimulate SGK.

Over 70% of breast cancers possess mutations that trigger activation of the PI3K (phosphoinositide 3-kinase) signalling pathway [ 1].

The Wright Fisher type model of Beerenwinkel et al. described the acquisition of driver mutations that trigger clonal expansions within a tumour.

The recent discovery of new, disease-associated mutations that trigger protein aggregation or stability represent unique opportunities to further dissect the effect and mechanism-of-action of protein aggregation in ALS.

Its researchers are studying families with a genetic mutation that triggers the early onset of Alzheimer's.

We investigated the nuclear mutational profile of oncocytic tumors to pinpoint the mutations that may trigger the early oncogenic hit.

Left unchecked, such damage can lead to genetic mutations that can trigger cancer.

Ancestral libraries therefore comprise a means of focusing diversity to positions and mutations that readily trigger changes in substrate and/or reaction specificity, thereby facilitating the isolation of new enzyme variants for a variety of different substrates and reactions by medium-throughput or even low-throughput screens.

Resistance to these drugs is the result of various somatic mutations that ultimately trigger aberrant phosphoinositide 3-kinase (PI3K /Akt activation [ 41].