Sentence examples for mutations of gene from inspiring English sources

Thirdly, mutations of gene regulated on apoptosis tend to be carcinogenic.

Cystic fibrosis (CF) is one of the most common fatal autosomal recessive disorders in the Caucasian population caused by mutations of gene for the cystic fibrosis transmembrane conductance regulator (CFTR).

5-MTHF and vitamin B12 supplementation might ameliorate RBC membrane features of children with CF. ClinicalTrials.gov NCT00730509 Cystic fibrosis (CF) is one of the most common fatal autosomal recessive disorders caused by mutations of gene for the cystic fibrosis transmembrane conductance regulator (CFTR), which is a member of the transporters acting as ATP-gated chloride channel [1] [6].

Because the mutations of gene NOTCH1 have been often observed in human T-ALL, we decided to check the mutational status of NOTCH1 in our transgenic model.

Recently, Ren and Xia have proposed four criteria to identify sperm ion channel proteins: detectability in sperm, preferably with knockout sperm as a negative control; ability to produce ion channel current detectable by patch-clamp recording; blocking of the channels that impairs normal sperm function; and mutations of gene encoding the ion channel proteins leading to sperm malfunctions [ 10].

Dr. Sulston described the visible steps in the cellular death process and demonstrated the first mutations of genes participating in programmed cell death, including a gene known as nuc-1.

Mutations of genes associated with the mismatch repair mechanism and mutations of the APC gene are the most frequent causes of hereditary colorectal cancer.

Germ-line mutations of genes responsible for repairing DNA mismatch may cause the transformation of chronic peptic ulceration to malignancy.

For women with high genetic susceptibility of cancer (e.g., mutations of genes BRCA 1, 2), oophorectomy is the only option for prevention.

Previous studies have shown that cases affected by FHM, carrying mutations of genes encoding ion channels (CACNA1A, ATP1A2, SCN1A), may have seizures [20 22].

Mutations of genes involved in epigenetic regulation are more prevalent in DS-ALL patients than non-DS ALL patients, highlighting the potential for alternative treatment strategies.