Sentence examples for mutations in prostate from inspiring English sources

"We have for the first time produced a comprehensive genetic map of the mutations in prostate cancers that have spread around the body.

Seven tumors, he says, is not a large enough sample to see the entire spectrum of mutations in prostate cancer.

The clinic's Lerner Research Institute had a total annual research expenditure of $255 million in 2012 and recently announced breakthroughs in creating a breast cancer vaccine, drugs to treat Alzheimer's patients and research into the genetic mutations in prostate cancer.

On the other hand, a recent study identified DLC1 mutations in prostate and breast cancers at particular tyrosine and serine residues.

The EPHB2 tyrosine kinase was first reported as a prostate cancer tumor suppressor gene, harboring somatic mutations in prostate tumors [15].

Huusko et al. recently described a variety of EPHB2 mutations in prostate tumours and in cell-lines [11], and a common nonsense mutation has been associated with prostate cancer in African American men with a family history of this disease [12].

The most common SPOP point mutation in prostate cancer involves the substrate-binding cleft of the gene.

The estimated frequency of the HOXB13 G84E mutation in prostate cancer families is influenced by the number of individuals in any given family as well as family structure.

The occurrence of PTEN mutation in prostate cancer is considered common, with reported frequencies (based on relatively small sample sizes), ranging from 30 to 60% (Whang et al, 1998; Kwabi-Addo et al, 2001).

This suggests that it is excellent for finding previously identified mutations, but perhaps not as useful for the identification of new mutations involved in prostate cancer metastasis.

This calls into question the conclusions of Sun et al. [ 9], who found these variants to be somatic mutations involved in prostate cancer.