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Breakthroughs in prostate cancer are uncommon.
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But breakthroughs in targeting suspect genes in prostate cancer have yielded a tsunami of new drugs, with 100 now in mid- to late-stage human trials, almost triple the number in 1997.
In 2005, Tomlins et al made the breakthrough discovery of the fusion of the TMPRSS2 and ERG genes in prostate cancer.
The strength of cancer outlier profile analysis was powerfully demonstrated by the identification of the TMPRSS2-ERG fusion oncogene in prostate cancers [14], considered a major breakthrough in cancer genetics.
We can envision that the cloud-supported translational bioinformatics endeavours will promote faster breakthroughs in the diagnosis and prognosis of prostate cancer.
The clinic's Lerner Research Institute had a total annual research expenditure of $255 million in 2012 and recently announced breakthroughs in creating a breast cancer vaccine, drugs to treat Alzheimer's patients and research into the genetic mutations in prostate cancer.
They already compete in prostate cancer therapy.
Screening is not only an issue in prostate cancer.
Prostate-specific membrane antigen (PSMA) is highly expressed on prostate epithelial cells and strongly up-regulated in prostate cancer.
The notable statistics lie in the increase in prostate toys.
ZIP1 is repressed in prostate cancer [11].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com