Sentence examples for mutations have contributed from inspiring English sources

RST is expected to be larger than FST if stepwise mutations have contributed to differentiation, as in the case of ancient isolation [ 29].

It will be interesting to see if other loss-of-function mutations have contributed to the loss of male competitive traits in C. elegans.

While this is not a formal proof, it strongly suggests that new mutations have contributed to the observed response to selection in 3 out of the 4 populations.

Given the assumption that many changes related to neural tissues have occurred since the most common ancestor of humans and chimpanzees, leading to the development of advanced cognition and language in humans, it is likely that many different types of mutations have contributed to differences in neural-related phenotypes.

Both ASSET and accelerated point mutations have contributed to the functional diversity of elapid 3FTXs; ASSET leads to major changes in the surface properties, resulting in targeting of new receptors, while accelerated point mutations lead to fine-tuning of binding to the same receptors through minor alterations of the surface charge and topology.

The characterization of activating mutations has contributed to the elaboration of a model involving the extracellular domain of the receptor as an inverse tethered agonist which, upon binding of the ligand, relieves the transmembrane domain from an inhibiting interaction and activates it.

Novel findings utilizing in vivo optical imaging and bigenic reporter mice that possess both GFAP- luciferase and the SOD1G93A mutation have contributed new insights into the pathobiology of ALS.

To further characterize how genomic and epigenomic mutations may have contributed to expression differences of TFs between PA I and AS II, AS III and GBM IV, we analyzed the individual signature-specific TFs for alterations of DNA methylation levels or gene copy number mutations in comparison to normal tissue.

Also, a single amino acid change, Ser80 → Ile, was detected in ParC (KP02784), and the combined effect of these mutations could have contributed to the high-level resistance to quinolones displayed by Kp13 as has been shown for other pathogenic bacteria [ 51].

Thus, subtler genome alterations within the Bc species-group, such as gene duplication, divergence and point mutations probably have contributed as much or more than horizontal gene transfer and genome reduction to the unique niche adaptations of individuals within the Bc species-group.

Another theoretical mechanism by which subject N1's mutation might have contributed to her airflow obstruction could relate to accelerated bradykinin (BK) metabolism.