Sentence examples for mutations has become from inspiring English sources

Therapy targeting specific somatic mutations has become an increasingly important part of cancer therapy over the past 20 years.

The analysis of KRAS mutations has become a prerequisite for anti-epidermal growth factor receptor therapy in patients with metastatic colorectal cancers.

With the development of tools for genomic analysis, the task of positional cloning ENU-induced mutations has become quite feasible, and this approach has recently been widely applied and highly productive.

Thus, sequencing of the relevant regions of the HIV genome for detecting drug resistance associated mutations has become standard-of-care.

Assessment of epidermal growth factor receptor (EGFR) mutations has become mandatory to choose the most active first-line treatment for patients with advanced non-small-cell lung cancer (NSCLC).

TILLING, based on chemically induced mutations, has become a method of choice for reverse genetics studies, because it can be applied to a broad range of organisms to scan for mutations in any gene of interest.

(Different types of mutation leave different genetic signatures, so analysis of genomes can reveal much about which sorts of mutations have become established in the past).

It also means that mutations will continue to occur even after previous beneficial mutations have become fixed.

Viral genomic mutations have become increasingly recognized as being associated with the outcome of chronic HBV infection.

Comparison of the selected sequences (Table 1a) showed that two amino acid substitutions dominated the selected population (N32D and D65V, present more than 35 times in 53 different sequences), while 11 other mutations had become selectively enriched (present more than 5 times in 53 different sequences).

A total of nine mutations have become prevalent since 2009 and currently are the dominant variants (Table 2).