Sentence examples for mutations has shown from inspiring English sources

Genetic mapping of das13 (one of the das mutations) has shown it to be in the region of the rnh gene encoding RNase H.

However, evaluation of telomere lengths of DNA samples of following generations of TERT mutations has shown a statistical trend toward further telomere shortening for three large kindreds.

Analysis of the ability of this microarray to detect known gene mutations has shown a 97% mutation detection rate for base substitutions.

Recently, a drug class called poly ADP ribose polymerase (PARP) inhibitors that targets cancers caused by BRCA mutations have shown promise in clinical trials treating breast cancer [52].

The mitochondrial protease OMI (also known as HtrA2) has been implicated in Parkinson's Disease (PD) and deletion or protease domain point mutations have shown profound neuropathologies in mice.

Knockdown and targeted mutations have shown that both CEBPA and CEBPB are important for ovulation and Cebpb-deficient mice are sterile presumably due to a granulosa cell defect [8].

Cancer therapies targeting defined functional mutations have shown clinical benefit.

Lung adenocarcinoma patients with EGFR gene mutations have shown a dramatic response to gefitinib.

These mutations have shown correlation only with familial not sporadic BC [ 118, 119].

Bone biopsies from patients with PLS3 mutations have shown cortical and trabecular osteoporosis with normal to low bone formation rates.

In contrast, while TP53 mutations have shown to predict response to cyclophosphamide high dose therapy, mutations in general have been associated with anthracycline resistance in human breast cancers.