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Exact(14)
DNA methylation may show greater heterogeneity than gene mutations because it is a reversible modification.
We were unable to test egl-19 null mutations, because it is an essential gene, necessary for muscle contraction (Lee et al. 1997).
Theoretically, the old DNA strand will have fewer mutations because it is used as a template and has undergone fewer replication cycles.
This contrast demonstrates that our method is useful to explore mutations because it is not only more cost-effective, but also less demanding in time and labor.
Importantly, mtDNA is especially susceptible to deletions, rearrangements and mutations because it is not bound by histones and lacks the extensive repair machinery present in the nucleus.
Complex I – NADH (reduced nicotinamide-adenine dinucleotide) dehydrogenase is exceptionally susceptible to defects due to mtDNA mutations, because it has the most subunits encoded by mtDNA.
Similar(46)
However, it is somewhat premature to compare the effects of different murine mutations because, to date, the mutations have not been systematically evaluated on a uniform genetic context.
This was a de novo mutation because it was not found in either parent.
Like humans, only one copy of the mutation is needed to cause this severe disease and no individuals have two copies of the mutation because it causes death of the developing embryo.
Intentional creation is unlike random mutation because it can happen at a more rapid rate with immediate correction if the trait doesn't succeed.
This is a unique mutation because it was neither found in 1918 and 1977 H1N1pdm viruses, nor was it found in the human, swine and avian IAVs.
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