Sentence examples for mutations and thereby from inspiring English sources

SNaPshot can detect potentially druggable mutations and thereby integrate rapid genomic analysis into clinical practice.

Recombination can play an important role in evolution by combining advantageous mutations and thereby assisting in their fixation [ 7, 14].

One hypothesis posits that HGT can restore genes inactivated by mutations and thereby prevent stochastic, irreversible deterioration of genomes in finite populations known as Muller's ratchet.

However, these alterations may affect not only the risk but also the pattern of somatically acquired mutations and thereby tumor biology.

For closely related genomes of asexual organisms, negative selection will not have enough time to "purify" the deleterious mutations and thereby leads to relatively high ω.

These many complicating possibilities are avoided in standard laboratory selection by use of stringent selection (often lethal) conditions that eliminate growth of small-effect mutations and thereby simplify genetic analysis.

The associated allele at these nearby genes "hitchhikes" alongside the spreading mutation and thereby decreases genetic variation in that region.

We therefore hypothesized that targeting the proteasome may inhibit degradation of Bim in mast cells with the D816V mutation and thereby induce apoptosis in the cells.

If our pigeon undergoes substantial genetic mutation, and thereby loses its beak, feathers, and wings, we may concede that it is no longer a pigeon (Keil, 1989; Rips, 1989).

Cre-mediated deletion of exon 2 and 3 led to a frameshift mutation and thereby eliminated the expression of Dpr1 gene in the brain tissues (Supplementary information, Figure S1A-S1B).

If simple sequence repeats are located in coding regions, and if they consist of motifs whose length is not a multiple of three, then a change in the number of repeats leads to a frame-shift mutation, and thereby to a complete loss of the amino acid sequence information.