Sentence examples for mutations and hence from inspiring English sources

NHEJ may introduce indels that cause frame shift mutations and hence the disruption of gene functions.

Recently, Tu et al., reported that tagging Cas9 with ubiquitin-proteasomal degradation signals can facilitate the degradation of Cas9, reducing mosaic mutations and hence increases its ability to modify genomes in non-human primate embryos (Tu et al., 2017).

And ultra-violet radiation (which promotes cataracts and skin caner in humans) also promotes plant mutations and hence the rate of tropical speciation is greater than anywhere else on the globe.

It should be noted that resistant strains that have low fitness may acquire compensatory mutations and hence increase their fitness over the long-term.

One explanation for this is that the parental line, STM91-01, is derived from a RT lung metastasis and may have acquired additional oncogenic mutations and hence greater resistance to growth inhibitory signals.

The parents of the patients, carrying only one of the six mutations and hence producing a total of at least 50% of the maximum Na+ current from the wild-type plus the affected allele, were either asymptomatic or presented with a mild cardiac rhythm disorder (first degree AV block) [16].

A significant challenge with the use of RT inhibitors is the development of resistance; because HIV replicates continuously at a very high rate, there are many chances for mutation and hence the emergence of a virus resistant to many drugs.

So the mix that's in there, the mix that's in the population already is relatively aggressive compared to this very passive mutation and so the incumbent, the relatively aggressive incumbents are doing very, very well on average against the mutation, and hence once again, this equality holds.

Moreover, due to high mutation rate in mtDNA, especially in the D-loop, it is not possible to account for reverse-mutations, and hence we cannot completely rule out selection with the methods used.

Most interesting was that one (2.9%) symptomatic female patient (patient A) was found to be homozygous carrier of the G428A mutation and hence a non-secretor.

The decrease in nephrin levels by siRNA lead to proteinuria and increased foot process width was consistent with other studies, where a mutation (and hence function) in one or more amino acids of nephrin were shown [23], [24].