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Courtship was observed during 0 3 hrs and 8 12 hrs circadian time (CT; light is on from 0 to 12 hr CT) when flies are most active [47], except for flies carrying the ninaB360d mutation, which were observed during 1 4 hrs CT, as courtship was significantly reduced in evenings (8 12 hrs CT).
We used the information available before 2003, with the exception of information about four eligible families segregating a deleterious BRCA1/ BRCA2 mutation, which were recruited by July 2003.
All mutations were identified by sequencing on Miseq, except a large deletion in BRCA1 and the CHEK2 c.1100delC mutation which were detected by MLPA.
Moreover, three out of five (60%) of NSCLC cells harboured a PI3KCA mutation, which were located in exon 9 or 20.
Autonomic dysfunction is sometimes observed in SCA6. Lee et al. reported two cases of parkinsonism with urinary incontinence in non-juvenile-onset parkinsonism with the SCA6 mutation, which were misdiagnosed as MSA [ 74].
In addition we selected two genes potentially inactivated by nonsense mutation which were located outside deleted areas, but showed high log2 ratios and no known splice variants (CSTA for the GP202 and INHBB for the IPA220 gastric cancer cell lines).
Similar(52)
When both parents are dwarves, their embryos have a 25percentt chance of normal height, a 50percentt chance of dwarfism, and a 25percentt chance of what is called a double dominant mutation, which is usually fatal soon after birth.
Dr. Underhill and his colleagues associate another mutation, which is common in India, Pakistan and Central Asia as well as Europe, with the people of the Kurgan culture who, according to one theory, expanded from southern Ukraine and spread the Indo-European languages.
For this work, the non-uniform self-adaptation mutation, which is a fitness-dependent mutation rate, is utilized.
We extensively analyzed p.Cys282Tyr mutation which is predicted as a destabilizing and is primarily associated with the HH.
The most common mutation in tRNALys is m.8344A>G missense mutation, which is the main cause of MERRF syndrome that accounts for 80% of affect individuals.
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