Sentence examples for mutation which had from inspiring English sources

NZ2114 was a novel plectasin mutant identified through a high-throughput mutation, which had improved potency against S. aureus and S. pneumoniae (Andes et al. 2009; Ostergaard et al. 2009) and high expression yield (2.39 g/l in the supernatant of Pichia pastoris) (Zhang et al. 2014).

In contrast, the S298E mutation, which had no effect on either cofactor-activated phosphorylation or affinity for chromatin, did not perturb the ability of Gro/TLE1 to inhibit neuronal differentiation (Fig. 7B E, cf. bars 2 and 8).

Sequencing showed the homozygous mutation, which had not been reported so far.

K71P mutation, which had a weaker effect on immunoblotting, also impaired the ability of RseP to cleave wild-type HA-MBP-YqfG during the 15 min chase period.

The Vav1Y3F/DH* protein contains a L213Q mutation which had previously been found to inactivate the GEF function of this domain [ 20, 32, 51].

The presence in Namibe of the -14010C lactase persistence mutation, which had only been previously found in Kenya and Tanzania [ 32], raises intriguing questions about the relationships between the East and Southwest African pastoral scenes.

Similarly, Hydroxyflutamide and other antagonists did not show any evidence of binding as an agonist in LNCaP cells harbouring the T877A mutation which has also been linked to paradoxical agonism53,54 (Supplementary Fig. S3b).

To investigate in Australian patients with glaucoma and normal controls the prevalence and associated phenotype of the WDR36 D658G mutation, which has previously been suggested to be a disease-causing mutation in pedigrees with primary open-angle glaucoma (POAG).

In addition, an amide-containing side chain (Asn193) and a loop in domain B (ΔIG mutation), which have been proven to be important for thermostability in corresponding position of other α-amylases, were also investigated.

Biopsy is recommended for non-steatotic HCAs less than 5 cm to look for β-catenin mutation, which has a high risk of malignant transformation and needs resection.

By chance alone, it might be that they are both carrying a European mutation which has come together in their child".