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Exact(5)
Under these conditions, L1s with age-1(hx546) mutation showed increased resistance to H2O2.
Additionally, patients carrying a heterozygous loss of function SR-BI mutation showed increased HDL plasma levels and reduced capacity for efflux of cholesterol from macrophages [31].
Muscle fibres from a patient harbouring the R1135H mutation showed increased depolarization tendency at normal and reduced extracellular potassium compatible with the diagnosis.
Fibroblasts from patients with m.3243A > G MTTL1 mutation showed increased basal Ca2+ levels and a sustained Ca2+ elevation in response to stimulation with 60 mM K+ compared with controls (Moudy et al., 1995).
Such observations were consistent with earlier work showing that the absence of the regulatory YceP protein increased biofilm formation in E. coli by repressing genes that control indole transport into the cell and that a trpE mutation showed increased biofilm formation [ 78].
Similar(55)
The mechanism of androgen insensitivity in the context of an AR mutation showing increased NC-TDI is unclear.
However, the mutants harboring these mutations showed increased MICs (minimum inhibitory concentration) as compared to wild type strains.
Phenotypic analysis of cells harboring these mutations showed increased growth rates in vivo [13], [14], and in vitro as well [13].
Remaining out of 18 mutations, 16 mutations showed the neutral effect on protein structure and 2 mutations showed increased stability of the structure.
The two evolved PA1 isolates with clcA promoter mutations showed increased levels of clcA mRNA compared to either the ancestor or the PA1 isolate with a wild type clcA promoter.
The Δspd1 cdc22-D57N double mutant showed increased mutation rates and was more sensitive to damaging agents, causing double-strand breaks (DSBs) stress compared to single mutants.
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