Sentence examples for mutation should result from inspiring English sources

Because the reciprocal FGFR1-FGFR1OP2 transcripts were not detected, it is likely that this insertion mutation should result in the null mutation of FGFR1OP2/wit3.0.

Indeed, modeling the G38A mutant of hsp15.5, we discovered that a G38A mutation should result in sterical clashes with bound RNA (Figure S3).

At the same time, the E64RP mutation should result in an increase in the population for the open state.

Why paternal inheritance of a GNAS mutation should result in PPHP in some families and POH in others is unclear.

Thus, it appears reasonable to assume that the 522G>A (m.1169G>A) mutation should result in a defective SSU and so we have assigned this mutation to the 'expectedly disruptive' category.

Thus, the two mutations should result in a substantial reduction in net charge near physiological pH, although the proteins were not clearly resolved on pH 3 10 isoelectric focusing gels (data not shown).

In the case of a fitness cost of resistance, the sequential acquisition of multiple deleterious resistance mutations should result in a cumulative fitness deficit that may reduce the likelihood that a strain will evolve extensive drug resistance.

We designed mutations that should result in either loss of IRES function or should be neutral, based on the predicted structure.

A nonsense mutation that results in truncated protein should lead to haploinsufficiency; a splicing site mutation or insertion/deletion should result in a frameshift that leads to a different protein product; a missense mutation may change the amino acid and cause a dominant negative effect.

As none of the three genes on the XSR6 chromosome revealed any trace of frameshift or stop mutations, their duplication should result in quantitative changes in canonical transcripts.

The central role of ATM in cell regulation suggests that a loss of function mutations in the ATM gene should result in broadly pleiotropic effects.