Sentence examples for mutation should produce from inspiring English sources
The mutation should produce a bulge, which will change the structure of the stem of the precursor miRNA, and will likely affect the site of Drosha cleavage in producing pre-miR-502 pre-miR-502 pre-miR-502
Furthermore, since every real mutation should produce complementary bands in the two detection channels, an immediate quality control of each signal is possible [ 18].
If this dynamic allosteric explanation is tenable, then weakening the interdomain contact via the I28A mutation should produce a different response in side-chain dynamics upon Cdc25C substrate binding.
The tm290 mutation should produce a protein containing the first 714 amino acids of FBN-1 followed by 224 novel amino acids before encountering a stop codon; the tm290 transcript may also be targeted for degradation by the non-sense mediated decay pathway (Mango, 2001).
Because the present mice were not reared under conditions of light deprivation, it does not necessarily follow that their mutations should produce blindness [ 34].
It is also not clear why mutation of a single allele should produce a dominant ataxia phenotype.
On the one hand asexual reproduction and somaclonal mutation tend to produce divergent lineages and should produce congruent groups between markers; on the other hand, many other processes tend to mix genomes and should produce incongruent groups between markers.
Our higher confidence prediction was: If there is R or K in 1 of these positions (no mutation, or switch: 279R or 437K), then a change to E in the other (279E or 437E) should produce VIABLE mutant.
However, new signal arising from point mutation are most likely deprived from enhancing elements and hence should produce transcript isoforms in very small quantities, especially if located downstream of a strong site.
When dealing with populations with large effective sizes or with very old mutations, combining linkage with probabilistic modelling of linkage disequilibrium evolution should produce the greatest accuracy.
The most likely explanation for this discrepancy is the presence of secondary mutations as a result of the mutagenesis process; it seems unlikely that similar alleles should produce such disparate effects.
