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Exact(5)
Because of these findings, molecular surveillance for this mutation is critical to assess the durability of SP for malaria prevention.
It is possible that this mutation is critical to survival of phosphine exposure, as mutations in this region were also found in other phosphine-resistant insects and nematodes [ 10].
The key question here is as to whether the mutation is critical to the pathogenesis of cancer and common across a set of cancers, or possibly a "passenger mutation" selected along with a more important other mutation.
Given that the mutation is critical to convert the coalescent estimates to biologically informative demographic parameters, a series of analyses were conducted using different mutation rates to establish a confidence interval of coalescent estimates (Fig. 6).
The reader familiar with previous hypotheses on the role of sex in evolution should note that this hypothesis is very different from the previous ones, because it connects sex and mutation while implying that the nonrandom aspect of mutation is critical: it allows selection to act on combinations of alleles at different loci as interacting wholes while having a heritable effect.
Similar(55)
The current paper holds that selection on interactions and nonrandom mutation are critical for adaptive evolution.
Nucleotide sequence of the ham5 locus from T. reesei QM6a and T. reesei RL1/A8-02 RL1/A8-02 the mutatincluding critheal for femutationtility.
Understanding the biological consequences of COL4A1 and COL4A2 mutations is critical to the development of personalized therapeutic strategies.
The ability to detect the full spectrum of mutations is critical to the success of targeted sequencing projects.
Identifying cancer-associated mutations (driver mutations) is critical for understanding the cellular function of cancer genome that leads to activation of oncogenes or inactivation of tumor suppressor genes.
Ultimately, an improved understanding of the clinical impact of PIK3CA mutations is critical for the development of optimally personalized therapeutics against breast cancer and other solid tumors.
Related(16)
abnormality is critical
transfer is critical
deployment is critical
move is critical
transformation is critical
mutation is important
mutation is random
mutation is standard
mutation is beneficial
mutation is lethal
mutation is likely
mutation has critical
mutation is unknown
mutation is bad
mutation is common
mutation is rare
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