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The second method for spreading a mutation is based on the principle of copying.

Really, the main idea of the proposed novel mutation is based on that each vector learns from the position of the top best and the bottom worst individuals among the entire population of a particular generation.

An alternative explanation for increased polyadenylation with the DSE mutation is based on the report from mammalian systems that the DSE can act as a binding site for a negative regulator of mRNA 3' processing and polyadenylation [52].

A well-established classification system for p53 mutation is based on its roles as a transcriptional factor.

Since the classification of L188Q as a type 1 mutation is based on a single small family [ 29], it is possible that this designation is incorrect.

Moreover, p53 overexpression can occur in the absence of mutation due to the accumulation of wild-type p53 in cancer cells (Cripps et al, 1994; Dix et al, 1994), again highlighting the potential for mis-assigning p53 mutations in MSI cancers if mutation is based on overexpression of p53 protein.

Similar(54)

The rationale for generating the Δ196 mutation was based on two main factors.

The operators of crossover and mutation are based on probabilities, so not all individuals will make crossover and/or mutation.

To exclude that the altered enzyme activities of the OXPHOS complex in the tumour tissue with the A3243G mutation are based on the presence of the VHL protein, we tested tumour tissues by Western blot analysis for VHL content.

In general, the prediction of cancer driver mutations is based on the conservation analysis of mutated sites (Capriotti and Altman, 2011; Carter et al., 2009; Kaminker et al., 2007).

The module for mutations is based on syntax patterns and the one for protein protein interactions relies on chunk parsing.

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