Sentence examples for mutation determines the from inspiring English sources

In both man and mouse, the severity of the PDX1 mutation determines the pancreatic phenotype.

In Nav1.4, the position of the S4 mutation determines the voltage range in which the omega current occurs.

The mutation determines the deletion of the entire exon (131 bp) in the RNA processing, causing a severe alteration of the protein structure and thus the disease.

13 This mutation determines the threshold pH of fusion and affects the thermal stability of HA due to intermonomer interactions between HA2 and HA1 in the stalk region of HA.

The novel S59P mutation determines the presence in the TNF-R1 of one more proline residue, which might interfere with three-dimensional receptor folding, since the distinctive cyclic structure of proline's side chain gives it an exceptional conformational rigidity and might cause a bend in the receptor's secondary amino acid structure [ 27].

Population genetics theory predicts that the product S = 4 Ne s (where Ne is the effective size of a population 54 and s the selection coefficient of a new mutation) determines the expectation for the number and frequencies of polymorphisms observed within species, as well as the amount of divergence between species.

Patients were categorised into established mutation groups according to their genotype with the less severe mutation determining the group (9).

The first selection level is that of individual self-replicating species, grouped in phenotypes, which, through selection and mutation, determine the population distribution of the quasispecies.

We hypothesize that location rather than number of non-conservative mutations determines the amyloidogenicity of light chains.

To shed light on the experimental conversion of a rigidly invariant code to a mutating code, the present study examined code mutations determining the propagation of Bacillus subtilis on Trp and 4-, 5- and 6-fluoro-tryptophans.

It is worth noting that, based on the network reconstruction, the three key mutations determining the slow acetylator haplotypes (T341C, G590A and G857A) tend to be more recent than mutations that do not modify the acetylator status.