Sentence examples for mutation renders the from inspiring English sources

The M766D mutation renders the enzyme incapable of supporting the temperature-sensitive strain at a non-permissive temperature.

The Bsdr1 mutation renders the plant shorter with fewer tillers, but not severely abnormal as is common with many gain-of-resistance mutants in Arabidopsis (Shirano et al. 2002; Vogel and Somerville 2000).

This mutation renders the enzyme inactive, since Asp102 is a catalytic residue.

This mutation renders the clock arrhythmic and the SDS-PAGE analysis indicates that KaiCI430A is hyper-phosphorylated (Fig. 3).

This insertion mutation renders the GH receptor nonfunctional and causes severe GH resistance, leading to suppression of peripheral IGF-1 and insulin levels.

Based on our current and previous [25] findings, we surmise that the defective trafficking, along with fragmentation of the Golgi complex [48] and increased apoptosis [49], [50], may be the underlying basis how the E50K optineurin mutation renders the patients predisposed to the glaucoma pathology.

The cdk9T212A mutation rendered the kinase insensitive to stimulation by Csk1 in vitro, and phenocopied csk1Δ in both its cold-sensitivity and poor growth on the minimal medium EMM [20].

Here, I show that mice engineered to carry a germline point mutation rendering the propeptide protease-resistant exhibit increases in muscle mass approaching those seen in mice completely lacking myostatin.

Although these findings were consistent with the point mutation rendering the latent myostatin complex resistant to activation by BMP-1/TLD proteases, it was important to rule out the possibility that the point mutation caused increased muscling by decreasing myostatin expression levels.

SKMEL13 melanoma cells carry the BRAF V600E) mutation rendering the ERK signalling pathway constitutively active.

The fact that no red fluorescent colonies are visible supports the conclusion that the mutation rendered the promoter nonfunctional.