Sentence examples for mutation involves the from inspiring English sources

The mutation involves the deletion of part of a gene on the surface of cells.

At the protein level, each mutation involves the replacement of three to four consecutive residues with alanine.

This particular mutation involves the change of the glutamic acid residue at position 545 of the protein to an alanine residue.

In this study, we report a mutation that affects the phosphorylation motif (DKTGT) of human ATP7A in an infant with MD; this mutation involves the substitution of the 1048 threonine residue with an isoleucine residue (p.T1048I).

The third MPN-specific mutation involves the myeloproliferative leukemia virus oncogene (MPL; located on chromosome 1p34) and has been described in 3% of patients with ET and 7% of those with PMF, and only rarely in PV.

In fact negative dominants, carrying a point mutation involving the catalytic site of the enzyme, accumulated isomerized-damaged proteins and, hence, were more sensitive to the pro-apoptotic stimulus.

One mutation involving the gene encoding for the β4 subunit (SCN4B) has been associated with LQT3 (Medeiros-Domingo et al. 2007).

Only one patient carried a K-Ras mutation involving the first base of codon 12, leading to the 12aGT change (GGT → aGT, Gly → Ser, G12S).

Thus, a single Na+ channel mutation involving the deletion of Lys (ΔK1500) is associated not only with LQT3 but also BrS and conduction system disease (16).

We amplified this arm and then modified it by introducing a single nucleotide mutation involving the replacement of cytosine with guanine on exon 13 in the location that corresponds to position number 1082 of the murine cDNA.

Given that a germline mutation involving the same amino acid has been reported as a cause of paraganglioma [p. (Asp92Tyr)], two mutant alleles— sdh4D98G and sdh4D98Y were constructed to compare the phenotypes associated with the different substitutions.