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The big question, of course, is whether the mutation could help the virus spread.
The researchers say that the mutation could help predict who will respond to SSRIs--selective serotonin reuptake inhibitors such as Prozac--which restore flagging serotonin levels in people with depression.
Additional studies considering the role of this mutation could help to elucidate the role of cigarette smoking in the development of follicular lymphomas.
Understanding the biology of this G51D SNCA mutation could help us to target pathways in PD, MSA and other synucleinopathies, which lead to neuronal and glial α-synuclein accumulation.
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In addition, peripheral cells and primary cultures were derived from CHM patients with variety of mutations could help to confirm if different mutations cause similar phenotypes.
Re-sequencing and functional studies of candidate mutations could help resolve this question.
Identifying pathways activated by RAS mutations could help in developing targeted treatments for tumors with RAS mutations [ 39].
In the study, mutations of p53 gene and K-ras gene codon 12, and promoter hypermethylation status of p16, RASSF1A, and APC1A gene, were also examined because these gene alterations had substantial role in pathogenesis of NSCLC and whether or not they correlated to EGFR mutations could help to further clarify the importance of EGFR mutations on pathogenesis of NSCLC.
The integration of PALB2 mutation testing into clinical practice is still in progress and strategies that effectively identify potential PALB2 mutation carriers could help facilitate this important process.
Given that several new pig models have been produced for studying neurodegeneration showing great promise for this field (Dolezalova et al., 2014), we also considered that production of a pig model carrying a familial AD mutation (APPsw) could help to provide further insight into the disease compared with current similar rodent models.
Their goal was to find the key mutations, which could help scientists quickly detect other Cipro-resistant strains in the future.
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