Boeke says the second mutation could be compensating for the first one by helping the mutated p53 protein fold more like the normal version.
The induced mutation could be inherited in the next generation.
Moreover, these effects of the mutation could be complemented.
The pvdD mutation could be complemented in trans, enabling design of plasmid-based systems for the generation of novel pyoverdines.
If that natural mutation could be mimicked in human blood cells, patients could be endowed with immunity to the deadly virus.
If that mutation could be isolated — if the genetic sequence could be discovered — then the boon for our poor suffering species would be immeasurable.
Indeed we show here that using EvaGreen dye and LNA probes, genomic DNA containing BRAF V600E mutation could be detected by fluorescence microscopy at low femtomolar concentrations.
A high PSAV in an individual with a BRCA2 mutation could be used as an indicator of presence of PrCa and therefore as an indication for prostate biopsy.
This indicates that the Smo mislocalisation phenotype associated with the R1747Q mutation could be related to an upstream defect in regulation of Ptch1 ciliary confinement.
In the third tolerant isolate (ITCC 913) no mutation could be detected in any of the nine known sites conferring tolerance to MBC.
The study also found that the gastrointestinal changes in mice caused by the SERT mutation could be prevented if during pregnancy their mothers were given prucalopride, a drug that mimics the ability of serotonin to stimulate nerve cell development.
