Sentence examples for mutation and resistance from inspiring English sources

Although there is little concern that Klebsiella or Acinetobacter might be weaponized, the basic science of their mutation and resistance could be useful in helping us to understand these threats.

Previous studies [39] [41] show that there does not seem to be any association between this mutation and resistance to PZA.

Whereas the structures of the S. pneumoniae topoisomerase IV and the M. tuberculosis DNA gyrase reaction core are very similar, our model allowed us to establish clear relationships between amino acid mutation and resistance phenotype in M. tuberculosis DNA gyrase.

The importance of these error-prone polymerases in generating mutation and resistance, combined with their relaxed fidelity, suggests the opportunity to inhibit these enzymes with small molecules.

A significant association was observed between the RDL mutation and resistance to dieldrin with an odds ratio of 39.4 (P < 0.0001) when comparing the allele counts between phenotypes.

Furthermore, a recent study suggests an association between an activating K-ras mutation and resistance to TRAIL-induced apoptosis in human pancreatic and lung cancer cell lines.

Could there be a deeper explanation for cancer's persistence and regenerative power beyond simple mutations and resistance?

There is a non-linear relationship between the number of mutations and resistance.

The strong point of this study is that we could identify original mechanistic properties of quinolone binding that clarify relationships between amino acid mutations and resistance phenotype.

Thus, no association between ATM mutations and resistance to paclitaxel therapy was recorded.

Frequencies of specific mutations and resistance patterns are shown in Table  1 for NNRTI-and PI- based cART.