Sentence examples for mutation and increased from inspiring English sources

The presence of HCC was associated with the double mutation and increased age.

Interestingly, a recent publication has cited an association between BRCA1 mutation and increased progesterone receptor signalling (Ma et al, 2006).

Furthermore, the age-dependent V(D J selection coincides with the progressive introduction of IgVH mutation and increased class-switch.

These findings were consistent with the lack of association observed between the BRAF mutation and increased risk of recurrence or cancer-related mortality on univariate and multivariate analyses.

Under 2.0% glucose conditions, the RLS of the fob1Δ cells was decreased by the sir2-S473E mutandon and increased by the sir2-S473A mutation.

Here we report a large study of nearly 2000 PrCa cases with varying ages of diagnosis to validate the potential association between germline BRCA2 mutation and increased risk of disease and to refine RR for PrCa among BRCA2 mutation carriers.

Therefore, adjustment threshold for calling a mutation and increasing the read depth in samples is required for each gene and can improve consistency.

An overall test of association for men and women together showed a statistically significant association between BRCA1/2 mutations and increased non-cancer mortality (p = 0.024).

A correlation between mtDNA mutations and increased ROS contents in primary leukemia cells isolated from patients has been shown [ 40].

High PKB activity in pancreatic cancer tumors is associated with resistance to apoptosis, higher rates of metastasis and mutations, and increased proliferation and uninhibited growth.

Cancer is commonly thought as the result of progressive accumulation of random mutations and increased deregulation of key molecular pathways (somatic mutation theory of carcinogenesis, SMT) [ 1].