Sentence examples for mutation and increases from inspiring English sources

The persistent oxidative stress causes DNA mutation and increases fibroblastic activity, leading to liver cirrhosis and carcinoma.

Advantages of sexual reproduction arise from genetic recombination in cross-fertilisation, which purges deleterious mutation and increases genetic variability in the population [ 8- 10], enhancing adaptation in a changing environment.

Background: The high rate of HIV-1 mutation and increasing resistance to currently available antiretroviral (ART) therapies highlight the need for new antiviral agents.

We find a strong association between CETP Asp442Gly (rs2303790), an East Asian-specific mutation, and increased risk of AMD (odds ratio (OR)=1.70, P=5.60 × 10 -22 10 -22

The presence of HCC was associated with the double mutation and increased age.

Interestingly, a recent publication has cited an association between BRCA1 mutation and increased progesterone receptor signalling (Ma et al, 2006).

Furthermore, the age-dependent V(D J selection coincides with the progressive introduction of IgVH mutation and increased class-switch.

Under 2.0% glucose conditions, the RLS of the fob1Δ cells was decreased by the sir2-S473E mutandon and increased by the sir2-S473A mutation.

Therefore, adjustment threshold for calling a mutation and increasing the read depth in samples is required for each gene and can improve consistency.

These findings were consistent with the lack of association observed between the BRAF mutation and increased risk of recurrence or cancer-related mortality on univariate and multivariate analyses.

Here we report a large study of nearly 2000 PrCa cases with varying ages of diagnosis to validate the potential association between germline BRCA2 mutation and increased risk of disease and to refine RR for PrCa among BRCA2 mutation carriers.