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Although these mutants were very efficient to convert low amount of exogenous DX, at higher DX levels they performed only slightly better.
In comparison to the original activity of pepsin, the kinetic constants of these mutants were very low with Km values of 4.10 and 2.10 mM, and k0 values of 22.2 and 18.0 min−18.0
Defects in synaptic growth as described in TBPH mutants were very often associated with alterations in synaptic bouton shape.
Because the properties of the H6- and G6-furin mutants were very similar, the first will not be discussed in the text below.
Surprisingly, the behaviours of ΔrecG ΔclpX and Δruv ΔclpX mutants were very different from each other despite both mutants being sensitive to 2-AP.
The original mutants were very stable as indicated by low rates of reversion to prototrophy.
Similar(48)
Resistant mutants are very rare, except for vancomycin-resistant Enterococcus.
We have also shown that serotonin mutants are very defective in their time allocation.
Thus, under conditions of nitrogen starvation, autophagy mutants are very sensitive to the extracellular pH, and more acidic medium leads to greater cell death.
We have shown that helicase defective dna2-2 mutares are very defective in X-ray repair, but the double sgs1Δ dna2-2 mutant is significantly more sensitive to IR than dna2-2, even though sgs1Δ itself is X-ray resistant [31].
Our TEM data presented here indicate that wild-type B. pseudomallei and the bopA and bipD mutants are very rarely found within double membrane autophagosomes and that the bopA mutant displays reduced phagosome escape.
Related(18)
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