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That language combined with Fouchier's remarks in interviews and sometimes hyperbolic press coverage appeared to suggest that the airborne mutants were extremely lethal, which "greatly alarmed" many NSABB reviewers, says virologist Robert Webster of St . Jude Childrens Research Hospital in Memphis, Tennessee, an influenza expert who was asked to advise NSABB on the two papers.
Amounts of the derivatives secreted by these mutants were extremely low, which may explain the dominant effect of wild-type PcrV on translocon assembly at the initial stage of erythrocyte infection.
Interestingly, these mutants were extremely sensitive to ICL agent mitomycin C (MMC) (48, 54– 54).
When they treated the same flies with hydrogen peroxide, however, they found that the DJ-1β mutants were extremely susceptible to early death.
While rsp5-ww1 mutants did not exhibit any observable temperature sensitivity defect, rsp5-ww2 and rsp5-ww3 mutants were extremely temperature sensitive and failed to grow at 38°C.
Similar(55)
Both the uvrA and recA mutants are extremely sensitive to UV irradiation [30], [31], and making them Lula lysogens does not increase this sensitivity further (for example, to the level of the extra sensitive uvrA recA double mutant [30], [31]) (Fig. 5A).
Double halA− slt− mutants are extremely sensitive to Mg2+.
Also, the responses in unc-31 mutants are extremely variable.
As shown in Fig. 8, the mtirx1- 1 mutants are extremely small (Fig. 8a and b).
These mutants are extremely dwarfed, male-sterile, and most importantly their seeds fail to germinate without exogenous gibberellin [ 5, 6].
Specifically, these mutants are extremely inefficient at sliding nucleosomes along a DNA fragment (Patel et al., 2011).
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