Sentence examples for mutants were severely from inspiring English sources

Of mutants in three amino acid biosynthetic pathways, only leu2 mutants were severely deficient in vivo.

As shown in Figure 7A, both the SUMO1(FV) and SUMO2(QFI) mutants were severely impaired in their ability to be attached to Pc2.

However, at 4°C, all four mutants were severely growth defective, and completely failed to grow both in liquid broth and on ABM-agar plates (Fig. 2B).

Approximately 20% of the analyzed mutants (24 mutants) were severely attenuated and 30% (35 mutants) were moderately attenuated in intraerythrocytic proliferation (Fig. 2B).

While ccs1Δ mutants grew relatively well in zinc-replete cells, these mutants were severely defective for zinc-limited growth (Fig. 3B).

In agreement with a previous report about Sep3 [15], we found that none of septin mutants were severely affected in virulence.

Mutants with defects in multiple D6PK genes such as d6pk double (d6pk01) double and d6pk d6pk012d6pkl2 (d6pk012) triple mutants are severely impaired in several developmental processes including tropic responses (d6pk01 and d6pk012) and lateral root differentiation (d6pk012) (Zourelidou et al., 2009; Willige et al., 2013).

This data supports and extends previous findings that germ cell migration to the gonads in sctt mutants is severely hindered but is successfully rescued when embryos express a wild-type copy of sctt [22].

Furthermore, the evapo-transpiration of esk1 mutants is severely reduced and their water use efficiency (WUE) i.e. the amount of carbon incorporated in biomass per water used, is higher than wild type.

Moreover, while a wild-type version of mammalian Hsp90α complements the budding yeast [19], [21], a Hsp90αΔ35 mutant, which can be considered intermediate between the two afore-mentioned yeast mutants, is severely defective for complementation (Morag McLean and DP, unpublished results).

In contrast, growth of Cgyap1Δ and Cgyap1Δ skn7Δ mutants was severely diminished in the presence of peroxynitrite.