Sentence examples for mutants of small from inspiring English sources

We also investigate the evolution of differentiation by examining the invasion of beneficial mutants of small effect that are linked to an already present, locally adapted allele.

DOI: http://dx.doi.org/10.7554/eLife.00994.009 10.7554/eLiFigure94.010 Figure 3 figure supplement 1. Viral sensitivity in a number of mutants of small RNA pathway genes.

These are local stability conditions: numerical evaluation of Rm is required to check that mutants of large effect could not invade even if mutants of small effect cannot.

The rate is determined primarily by the distribution among mutants of small effect; mutants with large deleterious effects are extremely unlikely to fix, and there can be few reversals of such fixations if they rarely happen in the first place.

Here, we combined fluorescence microscopy analyses, FLIM-FRET, cryo-electron microscopy and immunodetection to discriminate effects of different mutants of small GTPases on Cx43 transport and Cx43 oligomerization in living cells.

The comparison of specific activity may facilitate recognizing a mutant of small improvement of activity, but is prevented from practicing by the lack of efficient methods for selective assay of a mutant protein in its lysate.

To recognize a mutant of small improvement of catalytic capacity, specific activity calculated from total proteins in a lysate is an index better than activity concentration; a practical threshold for comparison to recognize a positive candidate can be the mean plus 1.4-fold SD of specific activities of the starting material.

It also demonstrates that an invasion analysis of mutants of very small effect is insufficient to obtain a full understanding of the evolutionary dynamics under frequency-dependent selection.

In this study, overexpression of the kinesin motor Unc-104/KIF1A Unc-104/KIF1Aaptureduced and could suppress the premature axonal acapturetions of AZ/SV prateins in mutands of the small, ARF-family G-protein Arl-8.

In the experiment, chondrocytes cultured in monolayers for 7 days were infected with the adenoviruses carrying CA or DN mutants of five small GTPases, and the attachment of the cells to fibronectin-coated plates was evaluated 3 days later.

To test if any Hfq-dependent sRNAs contribute to the virulence regulation, we constructed deletion mutants of 15 small RNAs identified in this study (Additional file 1: Table S1).