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However, the dOpa1+/− mutants exhibited lower locomotive indexes after the heat shock and were unable to recover within one hour.

In contrast, all three engineered virus mutants exhibited lower neuroinvasiveness as determined by morbidity rates (Fig. 4C).

When compared to the positive control strain, levQ/BSCZ/pMSP1781, a majority of the mutants exhibited lower expression from the fruA promoter when induced by fructose.

In addition, the mutants exhibited lower overall velocities and increased backward locomotion.

Collectively, REKs which expressed the G60S, G138R and fs260 ODDD-linked mutants exhibited lower transepithelial resistance when compared with ectopic Cx43-expressing REKs.

While mutations in α-I do not affect P/T binding or fidelity significantly, several α-H mutants exhibit lower binding affinity, processivity and frameshift fidelity [9] [12].

The correlation of mutations with GSs of the PI3K pathway suggests that PIK3CA mutants exhibit lower mTORC1 signalling and reduced PI3K activity, despite their oncogenic nature in vitro.

lin-41 (tn1487 ts ) mutants exhibit lower rates of M-phase entry at the end of pachytene, relative to lin-41 (null) alleles (Table 2), which permits some (at 25°) or most (at 22°) lin-41 (tn1487 ts ) mutant oocytes to progress through diplotene and into diakinesis.

When PK E6/E7 VECL cells were infected with low numbers (2000 and 5000) of C. albicans, the hxk1Δ mutant exhibited lower cytotoxicity as compared to the parental strain DIC185 considered as wild type and 6(b)).

The other mutants also exhibited lower fluorescence intensity at 325 nm compared to that of WT.

Mutant males exhibited lower frequency of fighting behaviors, including lunging and fencing and were often observed sharing the food patch after a few encounters.