Sentence examples for mutants can lead from inspiring English sources

Although a few variants present severe clinical symptoms in homozygotes, co-existence of heterozygous mutants can lead to deleterious conditions.

Stability evaluation of many mutants can lead to a better understanding of the sequence determinants of a structural motif and of factors governing protein stability and protein evolution.

Increase of these mutants can lead to loss of Wolbachia infections, either as a direct consequence of their increase or in a step-wise manner, and we derive analytically a threshold penetrance above which a mutation's spread leads to extinction of Wolbachia.

Both reports find that OGA null mutants can lead to a life extension phenotype, but under somewhat different circumstances.

The non-functional proteins present in the dominant mutants can lead to a complete block of activity, equal to the one seen in the leo k.o. ; luc k.o.o

According to previous data, a mutation can lead to either oxidation-mimicking mutants, if cysteins are exchanged by glycine, or oxidation-resistant mutants bearing alanine at the corresponding cysteins.

Our results show that the point mutants S503A/T251A can lead to improvement in gene delivery and minimal change in tissue tropism.

Relatively subtle changes in the proportion of mutant mtDNA can lead to dramatic effects on a patient's phenotype; however, the mtDNA mutation doesn't do it alone.

However, it is unclear why alterations in fatty acid metabolism in SACPD-C mutant nodules can lead to premature nodule senescence.

Lu et al. reported that silencing of mot-2 in hepatocellular carcinoma (HCC) cells with mutant p53 can lead to apoptosis.

SOD1 encodes a protein that is responsible for reducing free oxygen radicals in the cytoplasm, and expression of mutant SOD1 can lead to oxidative stress, which could form the basis of motor neuron death in ALS.