Sentence examples for mutants can result from inspiring English sources

Such correlations may explain aspects of lifespan evolution, and why loss-of-function mutants can result in lifespan extension.

However, R mutants can result from mutations affecting O-PS precursor synthesis, its polymerization and transport or from a variety of defects in the inner core oligosaccharide.

This reveals new insight that longevity assurance in daf-2 mutants can result from convergent regulation of vitellogenesis by pleitropic phenotypes in these mutants.

Neuronal cultures systems have shown that superinfection of latently infected cells with an IE null mutant can result in reactivation possibly via delivery of VP16 although less efficiently than with a similar mutant able to express ICP0 (Terry-Allison et al., 2007).

Furthermore, we show that an acceptor-splice site mutation can result in different mutant transcripts, including a two-exon-skip involving an upstream exon.

This persistence of a Mad linker regulation by phosphorylation could explain results in the literature showing that Mad10 mutant clones can result in Wg-like effects in the Drosophila wing [36].

We observed that SOD2 overexpression in rbf1 mutant eyes can result in ommatidial clusters with extra interommatidial cells (Fig. 6B).

High concentrations of mutant mtDNA can result in a variety of mitochondrial disorders, which can cause severe suffering and premature death.

Two studies showed that both knockdown of PTEN and transfection of mutant PIK3CA can result in lapatinib resistance and the mTOR/PI3K inhibitor, NVP-BEZ235 can reverse the resistance [ 26, 50].

The significance of the transcriptional regulation of MKKs is also supported by several observations that overexpression of wild type forms of the MKK genes in transgenic plants or increased expression in activation-tagged mutant plants can result in altered resistance against a range of pathogens [ 60- 62].

Thus, compromised biological function of HDAC8 mutants in CdLS can result from diminished thermostability as well as compromised catalytic activity.