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In addition, we found a floral organ number increase in dp1 mutants at low penetration.

In several mutants at low substrate concentrations, the maximum level of ampicillin production was increased up to 1.5-fold, and the ratio of the synthetic rate over the hydrolytic rate was increased 5 15-fold.

The abdominal wall defect is seen in both Vangl2 Lp/Lp and Celsr1 Crsh/Crsh mutants, at low incidence (<5% and ~10%, respectively).

It should be noted that the essential character of the early proton release has not been proven, as BR retains its proton-pumping activity even when proton release occurs after uptake, as happens in a number of BR mutants, at low pH and in some close homologues of BR.

Similar(56)

Interestingly, SD treatments did not promote heading in the mutant; however, the LD treatment promoted heading in the mutant at low temperatures.

A little unexpectedly, we found that both the trimeric and dimeric enzymes of E. coli, RecBCDEc and RecBCEc (lacking RecD), were competent not only to protect the ΔrecCBD strain of P. syringae from UV and MMC treatment, but also in supporting the growth of the mutant at low temperature, suggesting that both RecBCDEc and RecBCEc complexes retain functional activity at 4°C.

Furthermore, the double mutant resembled the tph-1 mutant at low bacterial levels and the daf-7 mutant at high bacterial levels, suggesting that these genes act in parallel rather than in a linear pathway.

Stabilization of substrate binding by the additional phenylalanine residue near the heme moiety in the I369F mutant via stacking interactions of the aromatic rings may contribute to the high rate of CBZ turnover observed with this mutant at low CBZ concentrations.

However the higher activity of the Tyr204 mutants observed at low pH is inconsistent with the proposal that such a tyrosinate ion acts to force IPP into a catalytically competent position, but rather backs up the theory that the stabilization of the PPi leaving group facilitated by the tri-nuclear Mg cluster helps drive the reaction  [12].

Quantitative pyrosequencing showed that the m.4175G>A mutation was present at high levels of heteroplasmy in skeletal muscle (90% mutant load); at low levels (5% mutant load) in a urinary sediment-derived DNA sample, but undetectable in all other DNA samples.

It is possible that our laboratory did not detect emergent mutants at a low level of replication because of the sensitivity of the test in this study.

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