Sentence examples for variants at low from inspiring English sources

Deep sequencing of 78 tumor specimens (≥1000× average unique coverage across the capture region) achieved high sensitivity for detecting somatic variants at low allele fraction (AF).

It has been observed that AB10 shows the probable results in terms of wear and friction characteristics as compared to other lubricant variants at low load and high sliding velocity conditions and perform as an excellent lubricant additive.

In general, it seems that there are no large differences in the intermodulation distortion behavior between the real and simulated AC30 variants at low- and medium gain settings.

This finding follows the Darwinian principle of 'survival of the fittest', in that drug-resistant variants at low levels can out-compete wild-type virus in presence of antiretroviral selection pressure and lead to treatment failure.

In summary, our results suggest the extended-dose NVP regimen used in the SWEN trial to prevent breast-milk transmission of HIV does carry a higher risk of infection with drug resistant virus than does SD-NVP in subtype C-infected infants, and that the risk of infection with NVP-R variants at low frequencies continues through the first year of life with breastfeeding.

NGS can detect variants at low frequencies, which would go undetected by standard sequencing methods [ 7].

These considerations apply to sporadic breast cancer but may also provide insights into the mechanisms of high-penetrance susceptibility genes since risk variants at low-penetrance loci also contribute to the risk of BRCA1 and BRCA2 mutation carriers [ 87].

In addition to a pro-apoptotic role of high levels of H2BE, we cannot exclude other roles for this olfactory-specific histone variant at low or moderate levels.

Increasing the proportion of the low acyl variant at low pH during gelation causes a large reduction in bulk modulus and work to fracture; the high acyl variant is much more resistant to the effects of acid during gelation.

The high- E FRET value for the P2−P3 variant at low Mg2+ concentrations (<100 μM) is ∼0.9, whereas the single E value for P2−P3 at high Mg2+ concentrations (≥1 mM) is ∼0.8.

Preliminary results from the Carey lab with the L415G variant at low temperatures are encouraging in that they show well-defined changes in the Raman spectra as the nucleotidyl transfer reaction proceeds.