Sentence examples for mutant was suppressed from inspiring English sources

When increasing amounts of wild-type and mutant Tob proteins were individually added to the CNOT7 deadenylase reaction system, the activity of CNOT7 in the presence of wild-type Tob and the K63A mutant was suppressed (Fig. 2H).

It is of interest that the dsDNA binding deficiency of the K60A mutant was suppressed by an additional lysine-to-alanine substitution on K27.

It is intriguing that substantially higher amounts of zinc in the growth medium are required to suppress the sod1Δ mutant than the tsa1Δ mutant; the low zinc growth defect of the tsa1Δ mutant was suppressed by as little as 10 µM added zinc [13] while the sod1Δ mutant required greater than 10-fold more zinc for suppression.

We also observed that the increased petite frequency in the erg26 mutant was suppressed by HU (Table 2).

Co-overexpression of pri-let-7a-1 mutants with Lin28a in HeLa cells followed by northern blotting against let-7a confirmed the importance of the AU dinucleotide adjacent to the GGAG motif in the Lin28a-mediated inhibition of let-7a processing, as only the pri-let-7a-1@2 mutant was suppressed to the same extent as the wild-type pri-let-7a-1.

However, the phenotype of the tpk2Δ mutant was suppressed in the triple mutant ssa1Δ ssasΔ tpk2Δ, as its HSE-dependent expression was higher than in tpk2Δ cells (at 25 °C and 39 °C), similar to that of the ssa1Δ and the WT at 25 °C, and lower compared to ssa1Δ and the WT at 39 °C.

Suppression is observed when expression changes elicited by one single mutant are suppressed by deletion of a second GSTF.

Only upon deletion of the repressor can buffering take place and the effects of the single mutant are suppressed.

The glucose growth and signaling defects of the tps1 mutant are suppressed by deletion of the most active hexokinase, Hxk2 (Hohmann et al., 1993).

Therefore, these observations strongly suggest that the up-regulation of cell death inducing genes in early stages of seed development in 3mlpa mutant is suppressed in late stages.

Similarly, the resection defect of the sae2 mutant is suppressed by yku70 in an Exo1-dependent manner (Limbo et al. 2007; Mimitou and Symington 2010).