Sentence examples for mutant might cause from inspiring English sources

The altered conformation observed in the Q212P mutant might cause a different affinity for cellular membranes and, consequently, an aberrant localization of PrP in the cell compartments, to favor formation of altered ER topologies [20], [21].

Low PE in the eas mutant might cause membrane leakiness or decrease ion channel activity, which in either case leads to the transient paralytic phenotype.

Thus, it seems that hyper-activation of the JA signalling pathway in the fou2 mutant might cause some changes in cell walls that do not occur in the infested wt plants.

Although enzymes for GlcNAc biosynthesis and chitin synthases showed hyphae specific (or low glucose inducible) expression at the mRNA level in our in vitro vulvovaginal candidiasis system, the lack of feeding this pathway with GlcNAc-6-PO4 in the hxk1Δ mutant might cause reduced chitin content for effective adherence [ 46].

There is no transgenic animal model for R135L rod opsin, but from the in vivo retinal R135L transduction data from Chuang et al. (14) and the data presented in this study, it can be inferred that the R135L mutant might cause cell death through the same mechanism.

Although this holds for receptors with two mutant subunits, it is conceivable that with three such substitutions, some degree of interaction between adjacent mutant subunits might cause deviations from the predicted curve shifts.

But ERK can be activated in other ways, and since most cancers involve a breakdown of the DNA-repair mechanism, which promotes mutation sooner or later a change arises that causes this to happen.Dr Thakur reasoned that if vemurafenib were withdrawn at this point, the extra ERK-stimulating signal from now-liberated mutant BRAF might cause ERK to be over-activated.

We examined whether over-expression of mutant strumpellin might cause a similar effect.

If increased levels of repetitive transcripts with dsRNA-forming potential do arise in the Adar1 mutant, these might cause the aberrant antiviral response.

In situ hybridization detecting the mature miRNA demonstrates that the mutation does not affect processing, suggesting that mutant miR-96 might cause hearing loss through a concomitant loss of function and gain of function.

Because the HOXA10 gene is expressed in the embryonic paramesonephric (Müllerian) ducts, abnormally low expression by mutant HOXA10 genes might cause CAUV.